Lysosomal activation and increased intracellular antibiotic accumulation accompanied reduced bacterial regrowth across mouse and human bladder epithelial models.
Higher ImP levels were associated with reduced transplant-free survival in PSC, while experimental models implicated p38 signaling in inflammation and fibrosis.
Investigators compared intra-articular microbial profiles and predicted metabolic pathways in patients with hip osteoarthritis and nonarthritic controls.