“We saw a need for practical guidance on the hospital-level systems, workflows, and practices that can strengthen the infection-related aspects of sepsis care throughout a patient's course.”
A nationwide cohort linked selected surgical procedures to higher odds of bacterial infection following firearm injury, while infection was not independently associated with mortality among those who survived 1 night of hospitalization.
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Biomarker-guided patient selection may help identify patients with sepsis who could benefit from endotoxin-targeted therapy, although confirmatory evidence is still needed.
In a planned BALANCE analysis, elevated day 7 procalcitonin was associated with higher mortality, but the small subgroup analysis found no evidence that extending antibiotics from 7 to 14 days improved outcomes.
A large Epic Cosmos analysis linked vaginal estrogen prescribing with lower rates of sepsis, hospital admission, and death following recurrent urinary tract infection, but researchers cautioned that prescribing may also mark broader differences in care.