Lower cortical disulfide bonding accompanied reduced tensile resistance with age, while follicular analyses identified COCH as a candidate molecular marker.
Patients carrying moderate- to high-risk breast cancer variants had poorer breast cancer–free survival, whereas polygenic risk scores did not improve prognostic stratification.
Exagamglogene autotemcel is now indicated for patients aged 2 years and older with sickle cell disease and recurrent vaso-occlusive crises or transfusion-dependent beta thalassemia.